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Merisis Biological Devices

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DiponEd, provide cost effective, reproducible, safe, and point-of-care devices which present an excellent option to patients for improving their own healing ability and minimizing the more intense way of managing the conditions.

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O-PRP

PRP used for ortho related issues.

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L-PRP

PRP used in hair related issues.

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P-PRP

PRP used in skin related issues.

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PRFM

Introducing “platelet-rich fibrin matrix” (PRFM) kit for the preparations of PRFM from peripheral blood. PRFM represents the only natural-based method of autologous tissue regeneration.

We at DiponEd follow a controlled process to convert Platelet Rich Plasma (PRP) to PRFM, thereby creating a fibrin matrix in the form of a gel that serves to protect and preserve platelets. This scaffolding helps in localized delivery of growth factors, essentially increasing the local concentration at the desired location to guide tissue regeneration.

Applications

  • Orthodontics
  • Periodontal regeneration
  • Sports injuries recovery
  • Anti-aging (skin)
  • Chronic wound healing
  • Non-healing ulcers
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PRFM – MerisisTM SuperCell Glue Kit – DFU

Platelet Rich Fibrin Matrix Therapy is a promising application in the field of periodontal regeneration and can be used in clinical situations requiring rapid healing. It also provides benefits in anti aging therapy and many other regenerative applications. It merges cutting-edge technology with the body’s natural ability to heal itself. Platelets contain packets of growth hormones and cytokines that trigger tissues repair, regeneration and enhance healing. When PRF is injected into the damaged area, it activates a mild inflammatory response, which triggers the healing cascade.

TM PRFM (DFU) Kit Product Competitiveness:

  • Compatible with most common clinical centrifuges
  • Easy separation due to the single tube use
  • Supplied with specific PRFM activators
  • Highly concentrated Platelets 2 to 4x extraction by centrifugation
  • Elimination of contamination, by adapting the enclosed system
  • Easy identification of the Buffy coat layer by naked eye
  • Gel separator minimizes RBC contamination
  • High count of number of platelets recovered
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PRFM – MERISISTM SUPERCELL GLUE KIT – DENTAL

Platelet Rich Fibrin Matrix (PRFM), is a biological matrix of ECM protein + growth factors derived from peripheral blood. MerisisTM Platelet rich fibrin matrix (PRFM) is a next generation biological product, made up of high concentrated platelets, Growth factors and natural fibrin speeding up the healing process. It merges cutting-edge technology with the body’s natural ability to heal itself.

PRFM is a fibrin matrix in which platelets, cytokines, growth factors and stem cells are trapped and released after a certain time, that can serve as a resorbable membrane or gel and helps in healing. PRFM mimics the natural healing environment in a tissue and enhances tissues repair and regeneration of cells and healing several times. When PRFM is applied into the damaged area, it activates a mild immune response, which triggers the healing cascade.

PRODUCT HIGHLIGHTS:

  • Simplicity - Only few steps required to prepare Fibrin Matrix.
  • Low blood volume required - It is designed to prepare autologous platelet concentrate from only 9ml of blood.
  • Platelet recovery - Recovers 90% platelets and a concentration factor of 3.8 fold.
  • Isolation of PRFM - Uses a physical barrier to separate the red blood cells from the plasma and the PRP.
  • Minimum contamination of RBC - 99.8% depletion of RBC
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CTC – KIT

Our CTC separation tube is a simple to use, rapid and efficient system for separation of disseminated circulating tumor cells from human peripheral blood. The system combines the advantages of the cell separation by density gradient centrifugation (rapid, reproducible, cost effective) with highest recovery rates.

It consists of a 13 ml glass tube with an inert polyester gel barrier inserted on top of the unique separation medium. It is perfectly suited to ensure routine and standardized enrichment of circulating tumor cells disseminated by a solid epithelial tumor or melanoma.

Competitiveness of DiponEd's CTC separation tubes:

  • Performance in about 30-45 minutes
  • Reproducible recovery rates: >70%
  • Depletion of blood cells up to 6 logs
  • No special lab requirement
  • Enrichment directly from whole blood
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MerisisTM   SuperCell+PRP (FEMI)

MerisisTM  Supercell +PRP (FEMI) Kit is a point of care, enclosed device for extraction of MNC’s (Mononuclear Cells) and Platelet Rich Plasma from the peripheral blood. It is an innovative treatment designed for females with reproductive disorders such as endometrial thinning and ovarian rejuvenation. The treatment uses point of care autologous PB-MNC stem cell with freshly prepared PRP and growth factors, which can reconstruct and regenerate tissue in vivo.

Applications

Endometrial thinning - FEMI Kit uses autologous MNC's extract and PRP providing growth factors for better proliferation and development of endometrial lining as it is highly regenerative in nature, therefore it regenerates faster.

Ovarian rejuvenation - PRP and stem cells stimulates the germ cell line developing into ovarian oocytes. Growth factors in activated platelets stimulate activation of resident stem cell present in ovaries that mature into oocytes.

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Merisis TM   SuperCell+PRP (ED)

MerisisTM Supercell +PRP ED Kit is a point of care, enclosed device for extraction of MNC’s (Mononuclear cells) and Platelet Rich Plasma from the peripheral blood. It is an innovative treatment designed for males with reproductive disorders such as

Erectile Dysfunction (ED).

The treatment uses point of care autologous PB-MNC stem cell with freshly prepared PRP and growth factors, which can reconstruct and regenerate tissue in vivo.

Applications

Erectile Dysfunction - This treatment utilizes patients own raw stem cells and growth factors to achieve natural male enhancement that help to regenerate erectile tissue and improves erections.

Also, it provides proper blood circulation in penile area, necessary for erectile tissue response.

Azoospermia/ Oligospermia – Azoospermia is a condition defined by total absence of sperm cells in the ejaculate whereras Oligospermia is a condition where less number of sperm cells are present. ED Kit separates MNC's that are multi potent cells having ability to regenerate into other different type of cells. Thus, MNC's + PRP can be used for Non-Obstructive Azoospermia and oligospermia .

Penile Enlargement – MNC's, PRP and growth factors are useful for tissue regeneration and healing, thus helpful in Penile Enlargement.

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BMSC KIT (BONE MARROW STEMCELL CONCENTRATE)

MerisisTM Ortho Supercell + Glue kit is developed to prepare concentrated MNC by centrifugation of the BM blood in a gel separator tube containing thixotropic gel acting as an inert barrier to increase the concentration of important nucleated cells while reducing the volume of the aspirate for added clinical utility. Kit Contains collection chamber, wash buffer for needle wash, anticoagulant, lower lock assembly, BM biopsy needle and also BM collection chamber Processing Unit, consisting of 6 Units MerisisTM Supercell glass tubes and 1 Unit MerisisTM PRFM (Glue) glass tube Preparation of Supercell tube containing – Thioxotropic gel and Ficoll, Sodium citrate Preparation of glue tube containing – Thioxotropic gel, Ficoll and activator (0.5ml Calcium Gluconate).

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PRP KIT

One-Step Gel Separation Technology

PRP, or Platelet Rich Plasma, is a biological substance made from peripheral blood to trigger healing and regeneration. Our approach is to merge cutting-edge technology with the body’s natural ability to heal itself. Platelets contain packets of growth hormones and cytokines that trigger tissues to repair and regenerate to enhance healing. When PRP is injected into the damaged area, it activates a mild inflammatory response, which triggers the healing cascade.

Competitiveness of DiponEd's PRP Kit

  • Compatible with most common clinical centrifuges
  • Easy separation due to the single tube use
  • Supplied with specific PRP activators
  • Highly concentrated PRP 2 to 4x extraction by centrifugation
  • Elimination of contamination, by adapting the enclosed system
  • Easy identification of the Buffy coat layer by naked eye
  • Gel separator minimizes RBC contamination
  • High count of number of platelets recovered

Types of Kit & Applications

  • L-PRP Kit (LEUOCYTE –Platelet Rich Plasma kit) contains white blood cells or leukocytes along with platelets - used to treat traumatic injuries
  • P-PRP Kit (Pure-Platelet Rich Plasma kit) separates pure PRP without leukocytes
    • Ortho PRP KIT: For Ortho applications, e.g., osteoarthritis, sprains, broken bone, etc.
    • Hair PRP Kit: Optimized growth factors for hair growth
    • Skin PRP Kit: Optimized growth factors for skin
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